Lipoma may be classified as a benign neoplasm that affects soft tissue2. This tumor is related to mature adipose tissue where it is commonly found in the mesenchymal region, according to the WHO classification.
Lipomas represent the most common mesenchymal tumors and are found in regions in which adipose tissue is normally present.
Occurrence of lipoma in the oral and maxillofacial cavity is rare; the frequency reported in the literature on oral lipoma (OL) is between approximately 15 to 5%6. These tumors can attack the tongue, lips, gingiva, floor of the mouth, salivary glands and oral mucosa.
Most OL are composed of mature fat cells, presenting as well-defined and covered by a thin, fibrous capsule4. Among the microscopic variations most commonly found are: classic lipoma, fibrolipoma, spindle cell lipoma, angiolipoma, salivary gland lipoma, and pleomorphic or atypical lipoma.
The purpose of the present study is to report a clinical case of a very extensive intra-oral lipoma, located in the mentonian region; also, to conduct a review of the literature about this tumor.